Biological determinants of bladder cancer gene expression subtypes.
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ABSTRACT:
SUBMITTER: Aine M
PROVIDER: S-EPMC4650643 | biostudies-literature | 2015 Jun
REPOSITORIES: biostudies-literature
Publications
Biological determinants of bladder cancer gene expression subtypes.
Aine Mattias M Eriksson Pontus P Liedberg Fredrik F Sjödahl Gottfrid G Höglund Mattias M
Scientific reports 20150608
Molecular stratification of tumors by gene expression profiling has been applied to a large number of human malignancies and holds great promise for personalized treatment. Comprehensive classification schemes for urothelial carcinoma have been proposed by three separate groups but have not previously been evaluated simultaneously in independent data. Here we map the interrelations between the proposed molecular subtypes onto the intrinsic structure of a rich independent dataset and show that su ...[more]
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