Ontology highlight
ABSTRACT:
SUBMITTER: Sengupta S
PROVIDER: S-EPMC4651072 | biostudies-literature | 2015 Dec
REPOSITORIES: biostudies-literature
Sengupta Sudeshna S Jonnalagadda Sudhakar S Goonewardena Lakshani L Juturu Veeresh V
Applied and environmental microbiology 20150911 23
cis,cis-Muconic acid (MA) is a commercially important raw material used in pharmaceuticals, functional resins, and agrochemicals. MA is also a potential platform chemical for the production of adipic acid (AA), terephthalic acid, caprolactam, and 1,6-hexanediol. A strain of Escherichia coli K-12, BW25113, was genetically modified, and a novel nonnative metabolic pathway was introduced for the synthesis of MA from glucose. The proposed pathway converted chorismate from the aromatic amino acid pat ...[more]