Ontology highlight
ABSTRACT:
SUBMITTER: Feng T
PROVIDER: S-EPMC4651624 | biostudies-literature | 2015 Nov
REPOSITORIES: biostudies-literature
Feng Tom T Sun Xizi X Howard Lauren E LE Vidal Adriana C AC Gaines Alexis R AR Moreira Daniel M DM Castro-Santamaria Ramiro R Andriole Gerald L GL Freedland Stephen J SJ Freedland Stephen J SJ
Cancer prevention research (Philadelphia, Pa.) 20150909 11
The role of metformin in prostate cancer chemoprevention remains unclear. REDUCE, which followed biopsy-negative men with protocol-dictated PSA-independent biopsies at 2- and 4-years, provides an opportunity to evaluate the link between metformin use and prostate cancer diagnosis with minimal confounding from screening biases. In diabetic men from REDUCE, we tested the association between metformin use, use of other antidiabetic medications, versus no antidiabetic medication use, and prostate ca ...[more]