Ontology highlight
ABSTRACT:
SUBMITTER: Frasinyuk MS
PROVIDER: S-EPMC4651832 | biostudies-literature | 2015 Dec
REPOSITORIES: biostudies-literature
Organic & biomolecular chemistry 20150929 46
The regiospecific Mannich aminomethylation of 7-hydroxyisoflavonoids using bis(N,N-dimethylamino)methane afforded C-8 substituted N,N-dimethylaminomethyl adducts, and the regioselective aminomethylation of 5-hydroxy-7-methoxyisoflavonoids afforded predominantly the C-6 substituted N,N-dimethylaminomethyl adducts. Acetylation of these C-6 or C-8 Mannich bases with potassium acetate in acetic anhydride provided access to the corresponding acetoxymethyl derivatives that were subsequently converted ...[more]