Ontology highlight
ABSTRACT:
SUBMITTER: Belone Ade F
PROVIDER: S-EPMC4653304 | biostudies-literature | 2015
REPOSITORIES: biostudies-literature
Belone Andrea de Faria F Ade F Rosa Patrícia S PS Trombone Ana P F AP Fachin Luciana R V LR Guidella Cássio C CC Ura Somei S Barreto Jaison A JA Pinilla Mabel G MG de Carvalho Alex F AF Carraro Dirce M DM Soares Fernando A FA Soares Cleverson T CT
Frontiers in genetics 20151120
Leprosy, an infectious disease caused by Mycobacterium leprae, affects millions of people worldwide. However, little is known regarding its molecular pathophysiological mechanisms. In this study, a comprehensive assessment of human mRNA was performed on leprosy skin lesions by using DNA chip microarrays, which included the entire spectrum of the disease along with its reactional states. Sixty-six samples from leprotic lesions (10TT, 10BT, 10BB, 10BL, 4LL, 14R1, and 10R2) and nine skin biopsies f ...[more]