Ontology highlight
ABSTRACT:
SUBMITTER: Hamshere S
PROVIDER: S-EPMC4654774 | biostudies-literature | 2015 Nov
REPOSITORIES: biostudies-literature
Hamshere Stephen S Arnous Samer S Choudhury Tawfiq T Choudry Fizzah F Mozid Abdul A Yeo Chia C Barrett Catherine C Saunders Natalie N Gulati Ankur A Knight Charles C Locca Didier D Davies Ceri C Cowie Martin R MR Prasad Sanjay S Parmar Mahesh M Agrawal Samir S Jones Daniel D Martin John J McKenna William W Mathur Anthony A
European heart journal 20150902 44
<h4>Aims</h4>The REGENERATE-DCM trial is the first phase II randomized, placebo-controlled trial aiming to assess if granulocyte colony-stimulating factor (G-CSF) administration with or without adjunctive intracoronary (IC) delivery of autologous bone marrow-derived cells (BMCs) improves global left ventricular (LV) function in patients with dilated cardiomyopathy (DCM) and significant cardiac dysfunction.<h4>Methods and results</h4>Sixty patients with DCM and left ventricular ejection fraction ...[more]