Ontology highlight
ABSTRACT:
SUBMITTER: Li S
PROVIDER: S-EPMC4655355 | biostudies-literature | 2015 Nov
REPOSITORIES: biostudies-literature
Li Shanshan S Li Tingting T Xu Yueyang Y Zhang Qionglin Q Zhang Wei W Che Shiyou S Liu Ruihua R Wang Yingying Y Bartlam Mark M
Scientific reports 20151123
YfiBNR is a tripartite signalling system in Pseudomonas aeruginosa that modulates intracellular c-di-GMP levels in response to signals received in the periplasm. YfiB is an outer membrane lipoprotein and presumed sensor protein that sequesters the repressor protein YfiR. To provide insights into YfiBNR function, we have determined three-dimensional crystal structures of YfiB and YfiR from P. aeruginosa PAO1 alone and as a 1:1 complex. A YfiB(27-168) construct is predominantly dimeric, whereas a ...[more]