Ontology highlight
ABSTRACT:
SUBMITTER: Ewing JR
PROVIDER: S-EPMC4656050 | biostudies-literature | 2015 Nov
REPOSITORIES: biostudies-literature
Ewing James R JR Nagaraja Tavarekere N TN Aryal Madhava P MP Keenan Kelly A KA Elmghirbi Rasha R Bagher-Ebadian Hassan H Panda Swayamprava S Lu Mei M Mikkelsen Tom T Cabral Glauber G Brown Stephen L SL
NMR in biomedicine 20151001 11
MRI estimates of extracellular volume and tumor exudate flux in peritumoral tissue are demonstrated in an experimental model of cerebral tumor. Peritumoral extracellular volume predicted the tumor exudate flux. Eighteen RNU athymic rats were inoculated intracerebrally with U251MG tumor cells and studied with dynamic contrast enhanced MRI (DCE-MRI) approximately 18 days post implantation. Using a model selection paradigm and a novel application of Patlak and Logan plots to DCE-MRI data, the distr ...[more]