Alcohol-induced dysregulation of stress-related circuitry: The search for novel targets and implications for interventions across the sexes.
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ABSTRACT:
SUBMITTER: Retson TA
PROVIDER: S-EPMC4656147 | biostudies-literature | 2016 Feb
REPOSITORIES: biostudies-literature
Publications
Alcohol-induced dysregulation of stress-related circuitry: The search for novel targets and implications for interventions across the sexes.
Retson T A TA Sterling R C RC Van Bockstaele E J EJ
Progress in neuro-psychopharmacology & biological psychiatry 20150523
While the ability to process fermented fruits and alcohols was once an adaptive trait that improved nutrition and quality of life, the availability and prevalence of high potency alcoholic drinks has contributed to alcohol abuse disorders in a vulnerable portion of the population. Although the neural reward systems take part in the initial response to alcohol, negative reinforcement and stress, which are normally adaptive responses, can intersect to promote continued alcohol use at all stages of ...[more]
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