Ontology highlight
ABSTRACT:
SUBMITTER: Cheng CY
PROVIDER: S-EPMC4656247 | biostudies-literature | 2012 Nov
REPOSITORIES: biostudies-literature
Cheng Chi-Yuan CY Goor Olga J G M OJ Han Songi S
Analytical chemistry 20121023 21
We introduce a new NMR technique to dramatically enhance the solution-state (13)C NMR sensitivity and contrast at 0.35 T and at room temperature by actively transferring the spin polarization from Overhauser dynamic nuclear polarization (ODNP)-enhanced (1)H to (13)C nuclei through scalar (J) coupling, a method that we term J-mediated (13)C ODNP. We demonstrate the capability of this technique by quantifying the permeability of glycine across negatively charged liposomal bilayers composed of dipa ...[more]