Ontology highlight
ABSTRACT:
SUBMITTER: Cooper SR
PROVIDER: S-EPMC4657173 | biostudies-literature | 2015 Nov
REPOSITORIES: biostudies-literature
Cooper Sharon R SR Emond Michelle R MR Duy Phan Q PQ Liebau Brandon G BG Wolman Marc A MA Jontes James D JD
The Journal of cell biology 20151101 4
Cell-cell recognition guides the assembly of the vertebrate brain during development. δ-Protocadherins comprise a family of neural adhesion molecules that are differentially expressed and have been implicated in a range of neurodevelopmental disorders. Here we show that the expression of δ-protocadherins partitions the zebrafish optic tectum into radial columns of neurons. Using in vivo two-photon imaging of bacterial artificial chromosome transgenic zebrafish, we show that pcdh19 is expressed i ...[more]