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ABSTRACT: Objectives
To evaluate the clinical characteristics and radiological features of solid pseudopapillary tumor (SPT) and assess surgical therapy strategy.Methods
A retrospective review was performed in 62 patients pathologically confirmed of SPT treated between 2003 and 2014. The clinical features, radiological examinations and surgical strategies were analyzed.Results
56 females and 6 males were included in this study, mean age was 26 years old (range: 8-66 years old) with mean size of the tumor was 7.2 cm (range: 3-15 cm), and most tumor were commonly located in the head of pancreas (n = 29). Among all the cases, 3 patients had liver metastasis and underwent resection of SPT and liver metastasis. Furthermore, we performed 29 cases of local tumor excision; other patients underwent pancreaticoduodenectomy, middle pancreatectomy, middle pancreatectomy with splenectomy, distal pancreatectomy with spleen preservation, distal pancreatectomy with splenectomy and duodenum-preserving pancreatic head resection. No patient suffered from lymph node metastases. After median follow-up of 46 months (range: 2-135 months), no mortality or local recurrence or distant metastasis was found.Conclusions
Solid pseudopapillary tumor is a latent malignant tumor with excellent prognosis. If feasible, less aggressive resection without regular lymphadenectomy is recommended for treatment of patients with SPT.
SUBMITTER: Zhang C
PROVIDER: S-EPMC4658154 | biostudies-literature | 2015
REPOSITORIES: biostudies-literature
Zhang Chi C Liu Fangfeng F Chang Hong H Li Hongguang H Zhou Xu X Lu Jun J Qin Chengkun C Sun Yongjie Y Sun Huidong H Lin Jianbo J
PloS one 20151123 11
<h4>Objectives</h4>To evaluate the clinical characteristics and radiological features of solid pseudopapillary tumor (SPT) and assess surgical therapy strategy.<h4>Methods</h4>A retrospective review was performed in 62 patients pathologically confirmed of SPT treated between 2003 and 2014. The clinical features, radiological examinations and surgical strategies were analyzed.<h4>Results</h4>56 females and 6 males were included in this study, mean age was 26 years old (range: 8-66 years old) with ...[more]