Ontology highlight
ABSTRACT:
SUBMITTER: Liu C
PROVIDER: S-EPMC4659144 | biostudies-literature | 2015
REPOSITORIES: biostudies-literature
Liu Chao C Tang Weifeng W Chen Shuchen S Wang Yafeng Y Qiu Hao H Yin Jun J Gu Haiyong H
International journal of clinical and experimental medicine 20150915 9
Esophageal cancer is the sixth leading cause of cancer-related deaths worldwide. It is very aggressive with a poor prognosis. Besides environmental risk factors, genetic factors might contribute to the esophageal cancer carcinogenesis. To evaluate the association between the risk of esophageal squamous cell carcinoma (ESCC) and genetic variants in IGFBP3, we conducted a hospital-based case-control study to assess the genetic effects of these SNPs. A total of 380 esophageal squamous cell carcinom ...[more]