Deep brain stimulation for chronic pain: intracranial targets, clinical outcomes, and trial design considerations.
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ABSTRACT:
SUBMITTER: Keifer OP
PROVIDER: S-EPMC4659490 | biostudies-literature | 2014 Oct
REPOSITORIES: biostudies-literature
Publications
Deep brain stimulation for chronic pain: intracranial targets, clinical outcomes, and trial design considerations.
Keifer Orion Paul OP Riley Jonathan P JP Boulis Nicholas M NM
Neurosurgery clinics of North America 20141001 4
For over half a century, neurosurgeons have attempted to treat pain from a diversity of causes using acute and chronic intracranial stimulation. Targets of stimulation have included the sensory thalamus, periventricular and periaqueductal gray, the septum, the internal capsule, the motor cortex, posterior hypothalamus, and more recently, the anterior cingulate cortex. The current work focuses on presenting and evaluating the evidence for the efficacy of these targets in a historical context whil ...[more]
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