Efficient synthesis of ?-conjugated molecules incorporating fluorinated phenylene units through palladium-catalyzed iterative C(sp(2))-H bond arylations.
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ABSTRACT: We report herein a two or three step synthesis of fluorinated ?-conjugated oligomers through iterative C-H bond arylations. Palladium-catalyzed desulfitative arylation of heteroarenes allowed in a first step the synthesis of fluoroaryl-heteroarene units in high yields. Then, the next steps involve direct arylation with aryl bromides catalyzed by PdCl(C3H5)(dppb) to afford triad or tetrad heteroaromatic compounds via regioselective activation of C(sp(2))-H bonds.
SUBMITTER: Abdelmalek F
PROVIDER: S-EPMC4661000 | biostudies-literature | 2015
REPOSITORIES: biostudies-literature
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