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Complete Genome Sequences of 11 Bordetella pertussis Strains Representing the Pandemic ptxP3 Lineage.

ABSTRACT: Pathogen adaptation has contributed to the resurgence of pertussis. To facilitate our understanding of this adaptation we report here 11 completely closed and annotated Bordetella pertussis genomes representing the pandemic ptxP3 lineage. Our analyses included six strains which do not produce the vaccine components pertactin and/or filamentous hemagglutinin.

SUBMITTER: Bart MJ 

PROVIDER: S-EPMC4661318 | biostudies-literature | 2015 Nov

REPOSITORIES: biostudies-literature

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Complete Genome Sequences of 11 Bordetella pertussis Strains Representing the Pandemic ptxP3 Lineage.

Bart Marieke J MJ   van der Heide Han G J HG   Zeddeman Anne A   Heuvelman Kees K   van Gent Marjolein M   Mooi Frits R FR  

Genome announcements 20151125 6

Pathogen adaptation has contributed to the resurgence of pertussis. To facilitate our understanding of this adaptation we report here 11 completely closed and annotated Bordetella pertussis genomes representing the pandemic ptxP3 lineage. Our analyses included six strains which do not produce the vaccine components pertactin and/or filamentous hemagglutinin. ...[more]

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