Dataset Information

Frequencies and Associations of Narcolepsy-Related Symptoms: A Cross-Sectional Study.

ABSTRACT: Narcolepsy is a disabling disease with a delayed diagnosis. At least 3 years before the disorder identification, several comorbidities can be observed in patients with narcolepsy. The early recognition of narcolepsy symptoms may improve long-term prognosis of the patients. Thus, we aimed to investigate the prevalence of the symptoms associated with narcolepsy and its social and psychological association in a sample of Sao Paulo city inhabitants.We performed a cross-sectional evaluation with 1,008 individuals from the Sao Paulo Epidemiologic Sleep Study (EPISONO). Excessive daytime sleepiness (EDS) was assessed by the Epworth Sleepiness Scale. Volunteers were also asked about the occurrence of cataplectic-like, hypnagogic or hypnopompic hallucinations, and sleep paralysis symptoms. The participants underwent a full-night polysomnography and completed questionnaires about psychological, demographic, and quality of life parameters.We observed a prevalence of 39.2% of EDS, 15.0% of cataplectic-like symptom, 9.2% of hypnagogic or hypnopompic hallucinations, and 14.9% of sleep paralysis in Sao Paulo city inhabitants. A frequency of 6.9% was observed when EDS and cataplectic-like symptoms were grouped. The other associations were EDS + hallucinations (4.7%) and EDS + sleep paralysis (7.5%). Symptomatic participants were predominantly women and younger compared with patients without any narcolepsy symptom (n = 451). Narcolepsy symptomatology was also associated with a poor quality of life and symptoms of depression, anxiety, and fatigue.Narcolepsy-related symptoms are associated with poor quality of life and worse psychological parameters.

SUBMITTER: Kim LJ

PROVIDER: S-EPMC4661329 | biostudies-literature | 2015 Dec

REPOSITORIES: biostudies-literature

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Frequencies and Associations of Narcolepsy-Related Symptoms: A Cross-Sectional Study.

Kim Lenise Jihe LJ Coelho Fernando Morgadinho FM Hirotsu Camila C Araujo Paula P Bittencourt Lia L Tufik Sergio S Andersen Monica Levy ML

Journal of clinical sleep medicine : JCSM : official publication of the American Academy of Sleep Medicine 20151215 12

<h4>Objectives</h4>Narcolepsy is a disabling disease with a delayed diagnosis. At least 3 years before the disorder identification, several comorbidities can be observed in patients with narcolepsy. The early recognition of narcolepsy symptoms may improve long-term prognosis of the patients. Thus, we aimed to investigate the prevalence of the symptoms associated with narcolepsy and its social and psychological association in a sample of Sao Paulo city inhabitants.<h4>Methods</h4>We performed a c ...[more]

PMID: 26235160

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Dataset Information

Frequencies and Associations of Narcolepsy-Related Symptoms: A Cross-Sectional Study.

Publications

Frequencies and Associations of Narcolepsy-Related Symptoms: A Cross-Sectional Study.

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