Ontology highlight
ABSTRACT:
SUBMITTER: Mondal PK
PROVIDER: S-EPMC4664191 | biostudies-literature | 2015 Mar
REPOSITORIES: biostudies-literature
Mondal Prolay K PK Liao Guochao G Mondal Mohabul A MA Guo Zhongwu Z
Organic letters 20150212 5
The structure of the capsular polysaccharide (CPS) of serotype Ia group B Streptococcus (GBS) has been characterized for years, but its repeating unit, which is a challenging pentasaccharide with a branch and a difficult α-sialic acid linkage, has not been synthesized yet. In this report, an effective synthesis was developed for the serotype Ia GBS CPS repeating unit, which had a reactive functionality linked to its main-chain reducing end to enable further elaboration, such as coupling with car ...[more]