Ontology highlight
ABSTRACT:
SUBMITTER: Valton E
PROVIDER: S-EPMC4665547 | biostudies-literature | 2015 Jan
REPOSITORIES: biostudies-literature
Valton Emeline E Amblard Christian C Desmolles François F Combourieu Bruno B Penault-Llorca Frédérique F Bamdad Mahchid M
Diagnostics (Basel, Switzerland) 20150112 1
In aquatic organisms, such as fish, blood is continually exposed to aquatic contaminants. Multidrug Resistance (MDR) proteins are ubiquitous detoxification membrane pumps, which recognize various xenobiotics. Moreover, their expression is induced by a large class of drugs and pollutants. We have highlighted the co-expression of a mini P-gp of 75 kDa and a P-gp of 140 kDa in the primary culture of brown trout erythrocytes and in the erythrocytes of wild brown trout collected from three rivers in ...[more]