Ontology highlight
ABSTRACT:
SUBMITTER: Isami S
PROVIDER: S-EPMC4666469 | biostudies-literature | 2015
REPOSITORIES: biostudies-literature
Isami Shuhei S Sakamoto Naoaki N Nishimori Hiraku H Awazu Akinori A
PloS one 20151201 12
Simple elastic network models of DNA were developed to reveal the structure-dynamics relationships for several nucleotide sequences. First, we propose a simple all-atom elastic network model of DNA that can explain the profiles of temperature factors for several crystal structures of DNA. Second, we propose a coarse-grained elastic network model of DNA, where each nucleotide is described only by one node. This model could effectively reproduce the detailed dynamics obtained with the all-atom ela ...[more]