Ontology highlight
ABSTRACT:
SUBMITTER: Soderhall C
PROVIDER: S-EPMC4666571 | biostudies-literature | 2015 Apr
REPOSITORIES: biostudies-literature
European journal of human genetics : EJHG 20140702 4
Hypospadias is a common male genital malformation and is regarded as a complex disease affected by multiple genetic as well as environmental factors. In a previous genome-wide scan for familial hypospadias, we reported suggestive linkage in nine chromosomal regions. We have extended this analysis by including new families and additional markers using non-parametric linkage. The fine mapping analysis displayed an increased LOD score on chromosome 8q24.1 and 10p15 in altogether 82 families. On chr ...[more]