Ontology highlight
ABSTRACT:
SUBMITTER: Carpenter C
PROVIDER: S-EPMC4666753 | biostudies-literature | 2015 Dec
REPOSITORIES: biostudies-literature
Carpenter Chelsea C Sidney John J Kolla Ravi R Nayak Kaustuv K Tomiyama Helena H Tomiyama Claudia C Padilla Oscar A OA Rozot Virginie V Ahamed Syed F SF Ponte Carlos C Rolla Valeria V Antas Paulo R PR Chandele Anmol A Kenneth John J Laxmi Seetha S Makgotlho Edward E Vanini Valentina V Ippolito Giuseppe G Kazanova Alexandra S AS Panteleev Alexander V AV Hanekom Willem W Mayanja-Kizza Harriet H Lewinsohn David D Saito Mayuko M McElrath M Juliana MJ Boom W Henry WH Goletti Delia D Gilman Robert R Lyadova Irina V IV Scriba Thomas J TJ Kallas Esper G EG Murali-Krishna Kaja K Sette Alessandro A Lindestam Arlehamn Cecilia S CS
Tuberculosis (Edinburgh, Scotland) 20150801 6
We compared T cell recognition of 59 prevalently recognized Mycobacterium tuberculosis (MTB) antigens in individuals latently infected with MTB (LTBI), and uninfected individuals with previous BCG vaccination, from nine locations and populations with different HLA distribution, MTB exposure rates, and standards of TB care. This comparison revealed similar response magnitudes in diverse LTBI and BCG-vaccinated cohorts and significant correlation between responses in LTBIs from the USA and other l ...[more]