Ontology highlight
ABSTRACT:
SUBMITTER: Kinnersley B
PROVIDER: S-EPMC4667278 | biostudies-literature | 2015 Dec
REPOSITORIES: biostudies-literature
Kinnersley Ben B Mitchell Jonathan S JS Gousias Konstantinos K Schramm Johannes J Idbaih Ahmed A Labussière Marianne M Marie Yannick Y Rahimian Amithys A Wichmann H-Erich HE Schreiber Stefan S Hoang-Xuan Khe K Delattre Jean-Yves JY Nöthen Markus M MM Mokhtari Karima K Lathrop Mark M Bondy Melissa M Simon Matthias M Sanson Marc M Houlston Richard S RS
Scientific reports 20151202
Genome-wide association studies (GWAS) have successfully identified a number of common single-nucleotide polymorphisms (SNPs) influencing glioma risk. While these SNPs only explain a small proportion of the genetic risk it is unclear how much is left to be detected by other, yet to be identified, common SNPs. Therefore, we applied Genome-Wide Complex Trait Analysis (GCTA) to three GWAS datasets totalling 3,373 cases and 4,571 controls and performed a meta-analysis to estimate the heritability of ...[more]