Ontology highlight
ABSTRACT:
SUBMITTER: Wu Y
PROVIDER: S-EPMC4667285 | biostudies-literature | 2015 Dec
REPOSITORIES: biostudies-literature
Wu Yunfei Y Wang Chengliang C Lin Shenglong S Wu Minhao M Han Lu L Tian Changlin C Zhang Xuan X Zang Jianye J
Acta crystallographica. Section D, Biological crystallography 20151126 Pt 12
Staphylococcus aureus is a Gram-positive bacterium with strong pathogenicity that causes a wide range of infections and diseases. Enolase is an evolutionarily conserved enzyme that plays a key role in energy production through glycolysis. Additionally, enolase is located on the surface of S. aureus and is involved in processes leading to infection. Here, crystal structures of Sa_enolase with and without bound phosphoenolpyruvate (PEP) are presented at 1.6 and 2.45 Å resolution, respectively. The ...[more]