Ontology highlight
ABSTRACT:
SUBMITTER: Bertol JW
PROVIDER: S-EPMC4667582 | biostudies-literature | 2015 Sep
REPOSITORIES: biostudies-literature
Bertol Jéssica Wildgrube JW Fregolente Maria Clara Duarte MC Caruzo Thabata Alessandra Ramos TA Silva Márcio José da MJ Munford Veridiana V Sáfadi Marco Aurélio Palazzi MA Rácz Maria Lucia ML Gatti Maria Silvia Viccari MS
Memorias do Instituto Oswaldo Cruz 20150901 6
Group A human rotaviruses (HuRVA) are causative agents of acute gastroenteritis. Six viral structural proteins (VPs) and six nonstructural proteins (NSPs) are produced in RV-infected cells. NSP4 is a diarrhoea-inducing viral enterotoxin and NSP4 gene analysis revealed at least 15 (E1-E15) genotypes. This study analysed the NSP4 genetic diversity of HuRVA G2P[4] strains collected in the state of São Paulo (SP) from 1994 and 2006-2010 using reverse transcription-polymerase chain reaction, sequenci ...[more]