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3D Printed Microtransporters: Compound Micromachines for Spatiotemporally Controlled Delivery of Therapeutic Agents.


ABSTRACT: Functional compound micromachines are fabricated by a design methodology using 3D direct laser writing and selective physical vapor deposition of magnetic materials. Microtransporters with a wirelessly controlled Archimedes screw pumping mechanism are engineered. Spatiotemporally controlled collection, transport, and delivery of micro particles, as well as magnetic nanohelices inside microfluidic channels are demonstrated.

SUBMITTER: Huang TY 

PROVIDER: S-EPMC4669391 | biostudies-literature | 2015 Nov

REPOSITORIES: biostudies-literature

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3D Printed Microtransporters: Compound Micromachines for Spatiotemporally Controlled Delivery of Therapeutic Agents.

Huang Tian-Yun TY   Sakar Mahmut Selman MS   Mao Angelo A   Petruska Andrew J AJ   Qiu Famin F   Chen Xue-Bo XB   Kennedy Stephen S   Mooney David D   Nelson Bradley J BJ  

Advanced materials (Deerfield Beach, Fla.) 20150928 42


Functional compound micromachines are fabricated by a design methodology using 3D direct laser writing and selective physical vapor deposition of magnetic materials. Microtransporters with a wirelessly controlled Archimedes screw pumping mechanism are engineered. Spatiotemporally controlled collection, transport, and delivery of micro particles, as well as magnetic nanohelices inside microfluidic channels are demonstrated. ...[more]

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