Dataset Information

Evaluation of the effectiveness of photodynamic therapy for the endodontic treatment of primary teeth: study protocol for a randomized controlled clinical trial.

ABSTRACT:

Background

The elimination of pathogenic microorganisms from the root canal system is one of the major steps required for successful endodontic treatment. The aim of the proposed study is to conduct a randomized, controlled, clinical trial for the clinical and radiographic evaluation of the effectiveness of photodynamic therapy during the endodontic treatment of primary teeth.

Methods

Thirty primary anterior teeth in children aged 3 to 6 years old will be randomly divided into 2 groups: a control group, which will receive conventional treatment, and an experimental group, which will be subjected to photodynamic therapy. Microbiological evaluations will be performed before and after endodontic treatment. Moreover, clinical and radiographic evaluations will be performed on the day of treatment as well as 1, 3 and 6 months after treatment. Comparisons will be made of the two study groups. The data will be tabulated and presented in a descriptive, analytical fashion. Depending on the distribution (normal or non-normal), either the t test, ANOVA or the Mann-Whitney test will be used for analysis of the variables. The Wilcoxon test will be used for comparisons before and after treatment. P values<0.05 (95% significance level) will be considered indicative of statistically significant differences.

Discussion

As successful endodontic treatment is directly related to intra-canal bacterial disinfection and considering the difficult task of endodontic treatment in primary teeth, often due to difficulties in controlling young children, the internal anatomy of root canals and root resorption, the alternative of using PDT is a painless,easy-to-administer method that does not lead to microbial resistance and can assist in the achievement of successful endodontic treatment in primary teeth by eliminating the pain children can experience due to retreatment as well as premature tooth loss.

Trial registration

The protocol for this study was registered with Clinical Trials number NCT02485210 on 30 july 2015.

SUBMITTER: da Mota AC

PROVIDER: S-EPMC4669610 | biostudies-literature | 2015 Dec

REPOSITORIES: biostudies-literature

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Publications

Evaluation of the effectiveness of photodynamic therapy for the endodontic treatment of primary teeth: study protocol for a randomized controlled clinical trial.

da Mota Ana Carolina Costa AC Gonçalves Marcela Leticia Leal ML Bortoletto Carolina C Olivan Silvia Regina SR Salgueiro Monica M Godoy Camila C Altavista Olga Maria OM Pinto Marcelo Mendes MM Horliana Anna Carolina AC Motta Lara J LJ Bussadori Sandra Kalil SK

Trials 20151203

<h4>Background</h4>The elimination of pathogenic microorganisms from the root canal system is one of the major steps required for successful endodontic treatment. The aim of the proposed study is to conduct a randomized, controlled, clinical trial for the clinical and radiographic evaluation of the effectiveness of photodynamic therapy during the endodontic treatment of primary teeth.<h4>Methods</h4>Thirty primary anterior teeth in children aged 3 to 6 years old will be randomly divided into 2 g ...[more]

PMID: 26635011

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Dataset Information

Evaluation of the effectiveness of photodynamic therapy for the endodontic treatment of primary teeth: study protocol for a randomized controlled clinical trial.

Background

Methods

Discussion

Trial registration

Publications

Evaluation of the effectiveness of photodynamic therapy for the endodontic treatment of primary teeth: study protocol for a randomized controlled clinical trial.

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