High sensitivity C-reactive protein (hsCRP) & cardiovascular disease: An Indian perspective.

ABSTRACT: The role of low grade systemic inflammation as evidenced by elevated high sensitivity C-reactive protein (hsCRP) levels in the pathogenesis of atherosclerotic vascular disease has been intensely investigated through observational studies and clinical trials in the past two decades. On the basis of evidence that has accrued, hsCRP measurement has been integrated into the Reynolds risk scoring system to predict cardiovascular risk. The JUPITER trial proved the benefit of statins in cardiovascular risk reduction in patients with low grades of systemic inflammation and 'normal' cholesterol levels. However, substantial evidence has been generated from western studies. We, therefore, conducted a scoping review for studies done in India with a view to identify gaps in evidence and make further re

SUBMITTER: Kamath DY 

PROVIDER: S-EPMC4669860 | biostudies-literature | 2015 Sep

REPOSITORIES: biostudies-literature