Ontology highlight
ABSTRACT:
SUBMITTER: Fan X
PROVIDER: S-EPMC4671015 | biostudies-literature | 2015 Dec
REPOSITORIES: biostudies-literature
Fan Xiaoqin X Xiong Haiting H Wei Jinmei J Gao Xuejuan X Feng Yuan Y Liu Xiaohui X Zhang Gong G He Qing-Yu QY Xu Jiake J Liu Langxia L
Scientific reports 20151207
Osteoclast differentiation is a complex and finely regulated physiological process that involves a variety of signaling pathways and factors. Recent studies suggested that the Ser9 phosphorylation of Glycogen synthase kinase-3β (GSK3β) is required for the osteoclast differentiation. However, the precise underlying mechanism remains unclear. We have previously identified the heterogeneous nuclear ribonucleoprotein K (hnRNPK) as a putative GSK3β interactor. In the present study, we demonstrate tha ...[more]