Ontology highlight
ABSTRACT:
SUBMITTER: Zugmaier G
PROVIDER: S-EPMC4671107 | biostudies-literature | 2015 Dec
REPOSITORIES: biostudies-literature
Zugmaier Gerhard G Gökbuget Nicola N Klinger Matthias M Viardot Andreas A Stelljes Matthias M Neumann Svenja S Horst Heinz-A HA Marks Reinhard R Faul Christoph C Diedrich Helmut H Reichle Albrecht A Brüggemann Monika M Holland Chris C Schmidt Margit M Einsele Hermann H Bargou Ralf C RC Topp Max S MS
Blood 20151019 24
This long-term follow-up analysis evaluated overall survival (OS) and relapse-free survival (RFS) in a phase 2 study of the bispecific T-cell engager antibody construct blinatumomab in 36 adults with relapsed/refractory B-precursor acute lymphoblastic leukemia (ALL). In the primary analysis, 25 (69%) patients with relapsed/refractory ALL achieved complete remission with full (CR) or partial (CRh) hematologic recovery of peripheral blood counts within the first 2 cycles. Twenty-five patients (69% ...[more]