Ontology highlight
ABSTRACT:
SUBMITTER: Rufino Ferreira AS
PROVIDER: S-EPMC4671637 | biostudies-literature | 2015 Jun
REPOSITORIES: biostudies-literature
Rufino Ferreira Ana S AS Hsia Justin J Arcak Murat M
IEEE life sciences letters 20150616 1
We propose a lateral inhibition system and analyze contrasting patterns of gene expression. The system consists of a set of compartments interconnected by channels. Each compartment contains a colony of cells that produce diffusible molecules to be detected by the neighboring colonies. Each cell is equipped with an inhibitory circuit that reduces its production when the detected signal is sufficiently strong. We characterize the parameter range in which steady-state patterns emerge. ...[more]