Ontology highlight
ABSTRACT:
SUBMITTER: Ma J
PROVIDER: S-EPMC4673245 | biostudies-literature | 2015 Aug
REPOSITORIES: biostudies-literature
Ma Jiguang J Duan Wanxing W Han Suxia S Lei Jianjun J Xu Qinhong Q Chen Xin X Jiang Zhengdong Z Nan Ligang L Li Jiahui J Chen Ke K Han Liang L Wang Zheng Z Li Xuqi X Wu Erxi E Huo Xiongwei X
Oncotarget 20150801 25
Ginkgolic acid (GA) is a botanical drug extracted from the seed coat of Ginkgo biloba L. with a wide range of bioactive properties, including anti-tumor effect. However, whether GA has antitumor effect on pancreatic cancer cells and the underlying mechanisms have yet to be investigated. In this study, we show that GA suppressed the viability of cancer cells but has little toxicity on normal cells, e.g, HUVEC cells. Furthermore, treatment of GA resulted in impaired colony formation, migration, an ...[more]