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A Petal-type Chiral NADH Model: Design, Synthesis and its Asymmetric Reduction.

ABSTRACT: A new type of NADH model compound has been synthesized by an efficient and convenient method. This model compound exhibits high reactivity and enantioselectivity in asymmetric reduction reactions. The results show that chiral NADH model S could be effectively combined with Mg(2+) to form ternary complexes. This novel C3 symmetrical NADH model is capable of fluorescence emission at 460 nm when excited at 377 nm.

SUBMITTER: Bai CB

PROVIDER: S-EPMC4673579 | biostudies-literature | 2015 Dec

REPOSITORIES: biostudies-literature

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A Petal-type Chiral NADH Model: Design, Synthesis and its Asymmetric Reduction.

Bai Cui-Bing CB Wang Nai-Xing NX Wang Yan-Jing YJ Xing Yalan Y Zhang Wei W Lan Xing-Wang XW

Scientific reports 20151209

A new type of NADH model compound has been synthesized by an efficient and convenient method. This model compound exhibits high reactivity and enantioselectivity in asymmetric reduction reactions. The results show that chiral NADH model S could be effectively combined with Mg(2+) to form ternary complexes. This novel C3 symmetrical NADH model is capable of fluorescence emission at 460 nm when excited at 377 nm. ...[more]

PMID: 26648413

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