Ontology highlight
ABSTRACT:
SUBMITTER: Gholizadeh M
PROVIDER: S-EPMC4673707 | biostudies-literature | 2015
REPOSITORIES: biostudies-literature
Gholizadeh Monireh M Khanahmad Hossein H Memarnejadian Arash A Aghasadeghi Mohammad Reza MR Roohvand Farzin F Sadat Seyed Mehdi SM Cohan Reza Ahangari RA Nazemi Ali A Motevalli Fatemeh F Asgary Vahid V Arezumand Roghaye R
Advanced biomedical research 20151029
<h4>Background</h4>Hepatitis C virus (HCV) infection is a serious public health threat worldwide. Cellular immune responses, especially cytotoxic T-lymphocytes (CTLs), play a critical role in immune response toward the HCV clearance. Since polytope vaccines have the ability to stimulate the cellular immunity, a recombinant fusion protein was developed in this study.<h4>Materials and methods</h4>The designed fusion protein is composed of hepatitis B surface antigen (HBsAg), as an immunocarrier, f ...[more]