Ontology highlight
ABSTRACT:
SUBMITTER: Sadhukha T
PROVIDER: S-EPMC4673890 | biostudies-literature | 2014 Sep
REPOSITORIES: biostudies-literature
Sadhukha Tanmoy T Wiedmann Timothy S TS Panyam Jayanth J
Biomaterials 20140616 27
Particle size is a key determinant of biological performance of sub-micron size delivery systems. Previous studies investigating the effect of particle size have primarily focused on well-dispersed nanoparticles. However, inorganic nanoparticles are prone to aggregation in biological environments. In our studies, we examined the consequence of aggregation on superparamagnetic iron oxide (SPIO) nanoparticle-induced magnetic hyperthermia. Here we show that the extent and mechanism of hyperthermia- ...[more]