Ontology highlight
ABSTRACT:
SUBMITTER: Kiczak L
PROVIDER: S-EPMC4676102 | biostudies-literature | 2015
REPOSITORIES: biostudies-literature
Kiczak Liliana L Tomaszek Alicja A Pasławska Urszula U Bania Jacek J Noszczyk-Nowak Agnieszka A Skrzypczak Piotr P Pasławski Robert R Zacharski Maciej M Janiszewski Adrian A Kuropka Piotr P Ponikowski Piotr P Jankowska Ewa A EA
Biology of sex differences 20151210
<h4>Background</h4>Although sex differences in heart failure (HF) prevalence and severity have been recognized, its molecular mechanisms are poorly understood. We used a tachycardia-induced cardiomyopathy model to determine the sex specific remodeling pattern in male and female adult pigs.<h4>Methods</h4>We compared the echocardiographic and molecular measures of myocardial remodeling in 19 male and 12 female pigs with chronic symptomatic systolic HF due to right ventricle (RV) pacing (170 bpm) ...[more]