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Improving Cancer Treatment via Mathematical Modeling: Surmounting the Challenges Is Worth the Effort.


ABSTRACT: Drug delivery schedules are key factors in the efficacy of cancer therapies, and mathematical modeling of population dynamics and treatment responses can be applied to identify better drug administration regimes as well as provide mechanistic insights. To capitalize on the promise of this approach, the cancer field must meet the challenges of moving this type of work into clinics.

SUBMITTER: Michor F 

PROVIDER: S-EPMC4676401 | biostudies-literature | 2015 Nov

REPOSITORIES: biostudies-literature

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Improving Cancer Treatment via Mathematical Modeling: Surmounting the Challenges Is Worth the Effort.

Michor Franziska F   Beal Kathryn K  

Cell 20151101 5


Drug delivery schedules are key factors in the efficacy of cancer therapies, and mathematical modeling of population dynamics and treatment responses can be applied to identify better drug administration regimes as well as provide mechanistic insights. To capitalize on the promise of this approach, the cancer field must meet the challenges of moving this type of work into clinics. ...[more]

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