Ontology highlight
ABSTRACT:
SUBMITTER: Neuner SM
PROVIDER: S-EPMC4677051 | biostudies-literature | 2015 Mar
REPOSITORIES: biostudies-literature
Neuner Sarah M SM Wilmott Lynda A LA Hope Kevin A KA Hoffmann Brian B Chong Jayhong A JA Abramowitz Joel J Birnbaumer Lutz L O'Connell Kristen M KM Tryba Andrew K AK Greene Andrew S AS Savio Chan C C Kaczorowski Catherine C CC
Behavioural brain research 20141213
Memory formation requires de novo protein synthesis, and memory disorders may result from misregulated synthesis of critical proteins that remain largely unidentified. Plasma membrane ion channels and receptors are likely candidates given their role in regulating neuron excitability, a candidate memory mechanism. Here we conduct targeted molecular monitoring and quantitation of hippocampal plasma membrane proteins from mice with intact or impaired contextual fear memory to identify putative cand ...[more]