The history of the CATH structural classification of protein domains.
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ABSTRACT:
SUBMITTER: Sillitoe I
PROVIDER: S-EPMC4678953 | biostudies-literature | 2015 Dec
REPOSITORIES: biostudies-literature
Publications
The history of the CATH structural classification of protein domains.
Sillitoe Ian I Dawson Natalie N Thornton Janet J Orengo Christine C
Biochimie 20150804
This article presents a historical review of the protein structure classification database CATH. Together with the SCOP database, CATH remains comprehensive and reasonably up-to-date with the now more than 100,000 protein structures in the PDB. We review the expansion of the CATH and SCOP resources to capture predicted domain structures in the genome sequence data and to provide information on the likely functions of proteins mediated by their constituent domains. The establishment of comprehens ...[more]
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