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Unveiling Bacterial Interactions through Multidimensional Scaling and Dynamics Modeling.


ABSTRACT: We propose a new strategy to identify and visualize bacterial consortia by conducting replicated culturing of environmental samples coupled with high-throughput sequencing and multidimensional scaling analysis, followed by identification of bacteria-bacteria correlations and interactions. We conducted a proof of concept assay with pine-tree resin-based media in ten replicates, which allowed detecting and visualizing dynamical bacterial associations in the form of statistically significant and yet biologically relevant bacterial consortia.

SUBMITTER: Dorado-Morales P 

PROVIDER: S-EPMC4680887 | biostudies-literature | 2015 Dec

REPOSITORIES: biostudies-literature

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Unveiling Bacterial Interactions through Multidimensional Scaling and Dynamics Modeling.

Dorado-Morales Pedro P   Vilanova Cristina C   P Garay Carlos C   Martí Jose Manuel JM   Porcar Manuel M  

Scientific reports 20151216


We propose a new strategy to identify and visualize bacterial consortia by conducting replicated culturing of environmental samples coupled with high-throughput sequencing and multidimensional scaling analysis, followed by identification of bacteria-bacteria correlations and interactions. We conducted a proof of concept assay with pine-tree resin-based media in ten replicates, which allowed detecting and visualizing dynamical bacterial associations in the form of statistically significant and ye  ...[more]

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