Influence of surface-imprinted nanoparticles on trypsin activity.
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ABSTRACT:
SUBMITTER: Guerreiro A
PROVIDER: S-EPMC4681057 | biostudies-literature | 2014 Sep
REPOSITORIES: biostudies-literature
Publications
Influence of surface-imprinted nanoparticles on trypsin activity.
Guerreiro António A Poma Alessandro A Karim Kal K Moczko Ewa E Takarada Jessica J de Vargas-Sansalvador Isabel Perez IP Turner Nicholas N Piletska Elena E de Magalhães Cristiana Schmidt CS Glazova Natalia N Serkova Anastasia A Omelianova Aleksandra A Piletsky Sergey S
Advanced healthcare materials 20140320 9
Here, the modulation of enzyme activity is presented by protein-imprinted nanoparticles produced using a solid-phase approach. Using trypsin as target, binding of the nanoparticles to the enzyme results in its inhibition or in stabilization, depending on the orientation of the immobilized enzyme used during imprinting. ...[more]
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