Ontology highlight
ABSTRACT:
SUBMITTER: Imaizumi K
PROVIDER: S-EPMC4682123 | biostudies-literature | 2015 Dec
REPOSITORIES: biostudies-literature
Imaizumi Kent K Sone Takefumi T Ibata Keiji K Fujimori Koki K Yuzaki Michisuke M Akamatsu Wado W Okano Hideyuki H
Stem cell reports 20151105 6
The CNS contains many diverse neuronal subtypes, and most neurological diseases target specific subtypes. However, the mechanism of neuronal subtype specificity of disease phenotypes remains elusive. Although in vitro disease models employing human pluripotent stem cells (PSCs) have great potential to clarify the association of neuronal subtypes with disease, it is currently difficult to compare various PSC-derived subtypes. This is due to the limited number of subtypes whose induction is establ ...[more]