Assessing the impact of engineered nanoparticles on wound healing using a novel in vitro bioassay.
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ABSTRACT:
SUBMITTER: Zhou EH
PROVIDER: S-EPMC4684260 | biostudies-literature | 2014 Dec
REPOSITORIES: biostudies-literature
Publications
Assessing the impact of engineered nanoparticles on wound healing using a novel in vitro bioassay.
Zhou Enhua H EH Watson Christa C Pizzo Richard R Cohen Joel J Dang Quynh Q Ferreira de Barros Pedro Macul PM Park Chan Young CY Chen Cheng C Brain Joseph D JD Butler James P JP Ruberti Jeffrey W JW Fredberg Jeffrey J JJ Demokritou Philip P
Nanomedicine (London, England) 20141201 18
<h4>Aim</h4>As engineered nanoparticles (ENPs) increasingly enter consumer products, humans become increasingly exposed. The first line of defense against ENPs is the epithelium, the integrity of which can be compromised by wounds induced by trauma, infection, or surgery, but the implications of ENPs on wound healing are poorly understood.<h4>Materials & methods</h4>Herein, we developed an in vitro assay to assess the impact of ENPs on the wound healing of cells from human cornea.<h4>Results & d ...[more]
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