Ontology highlight
ABSTRACT:
SUBMITTER: Neel BA
PROVIDER: S-EPMC4685069 | biostudies-literature | 2015
REPOSITORIES: biostudies-literature
Neel Brian A BA Zong Haihong H Backer Jonathan M JM Pessin Jeffrey E JE
Frontiers in physiology 20151221
Muscle wasting that occurs during aging or from disease pathology presents with an accumulation of lipid species termed ceroid or lipofuscin. This unique species of lipid has been characterized in various cell types but its properties and organization in skeletal muscle remains unclear. Using immunofluorescence and transmission electron microscopy, we were able to visualize and characterize an atypical lipid storing organelle in skeletal muscle. White myofibers contain two organelles at each pol ...[more]