Using aptamers to elucidate esophageal cancer clinical samples.
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ABSTRACT:
SUBMITTER: Liu Z
PROVIDER: S-EPMC4685197 | biostudies-literature | 2015 Dec
REPOSITORIES: biostudies-literature
Publications
Using aptamers to elucidate esophageal cancer clinical samples.
Liu Zhenxu Z Lu Yi Y Pu Ying Y Liu Jun J Liu Bo B Yu Bo B Chen Ke K Fu Ting T Yang Chaoyong James CJ Liu Huixia H Tan Weihong W
Scientific reports 20151221
The epithelial cell adhesion molecule (EpCAM) is closely correlated with the occurrence and development of various cancers of epithelial origin. This study tested, for the first time, the ability of EpCAM aptamer SYL3C to detect EpCAM expression in 170 cases of esophageal cancer (EC) and precancerous lesions, as well as 20 cases of EC series samples, using immunofluorescence imaging analysis. Corresponding antibodies were used as control. EpCAM overexpression was 98% in both esophageal squamous ...[more]
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