Ontology highlight
ABSTRACT:
SUBMITTER: Luzon-Toro B
PROVIDER: S-EPMC4685628 | biostudies-literature | 2015
REPOSITORIES: biostudies-literature
Luzón-Toro Berta B Bleda Marta M Navarro Elena E García-Alonso Luz L Ruiz-Ferrer Macarena M Medina Ignacio I Martín-Sánchez Marta M Gonzalez Cristina Y CY Fernández Raquel M RM Torroglosa Ana A Antiñolo Guillermo G Dopazo Joaquin J Borrego Salud S
BMC medical genomics 20151221
<h4>Background</h4>The molecular mechanisms leading to sporadic medullary thyroid carcinoma (sMTC) and juvenile papillary thyroid carcinoma (PTC), two rare tumours of the thyroid gland, remain poorly understood. Genetic studies on thyroid carcinomas have been conducted, although just a few loci have been systematically associated. Given the difficulties to obtain single-loci associations, this work expands its scope to the study of epistatic interactions that could help to understand the genetic ...[more]