Ontology highlight
ABSTRACT:
SUBMITTER: Weng NP
PROVIDER: S-EPMC4686144 | biostudies-literature | 2012 Mar
REPOSITORIES: biostudies-literature
Weng Nan-ping NP Araki Yasuto Y Subedi Kalpana K
Nature reviews. Immunology 20120316 4
How the immune system remembers a previous encounter with a pathogen and responds more efficiently to a subsequent encounter has been one of the central enigmas for immunologists for over a century. The identification of pathogen-specific memory lymphocytes that arise after an infection provided a cellular basis for immunological memory. But the molecular mechanisms of immunological memory remain only partially understood. The emerging evidence suggests that epigenetic changes have a key role in ...[more]