Ontology highlight
ABSTRACT:
SUBMITTER: Bonella F
PROVIDER: S-EPMC4686227 | biostudies-literature | 2015
REPOSITORIES: biostudies-literature
Bonella Francesco F Stowasser Susanne S Wollin Lutz L
Drug design, development and therapy 20151214
Idiopathic pulmonary fibrosis (IPF) is the most common type of idiopathic interstitial pneumonia and is characterized by a poor prognosis, with an estimated 5-year survival of approximately 20%. Progressive and irreversible lung functional impairment leads to chronic respiratory insufficiency with a severely impaired quality of life. In the last 2 decades, novel treatments for IPF have been developed as a consequence of an increasing understanding of disease pathogenesis and pathobiology. In IPF ...[more]