Ontology highlight
ABSTRACT:
SUBMITTER: Wu H
PROVIDER: S-EPMC4686680 | biostudies-literature | 2015 Dec
REPOSITORIES: biostudies-literature
Nature communications 20151208
A widely appreciated aspect of developmental robustness is pattern formation in proportion to size. But how such scaling features emerge dynamically remains poorly understood. Here we generate a data set of the expression profiles of six gap genes in Drosophila melanogaster embryos that differ significantly in size. Expression patterns exhibit size-dependent dynamics both spatially and temporally. We uncover a dynamic emergence of under-scaling in the posterior, accompanied by reduced expression ...[more]