SLOPE-ADAPTIVE VARIABLE SELECTION VIA CONVEX OPTIMIZATION.

ABSTRACT: We introduce a new estimator for the vector of coefficients ? in the linear model y = X? + z, where X has dimensions n × p with p possibly larger than n. SLOPE, short for Sorted L-One Penalized Estimation, is the solution to [Formula: see text]where ?1 ? ?2 ? … ? ? p ? 0 and [Formula: see text] are the decreasing absolute values of the entries of b. This is a convex program and we demonstrate a solution algorithm whose computational complexity is roughly comparable to that of classical ?1 procedures such as the Lasso. Here, the regularizer is a sorted ?1 norm, which penalizes the regression coefficients according to their rank: the higher the rank-that is, stronger the signal-the larger the penalty. This is similar to the Benjamini and Hochberg [J. Roy. Statist. Soc. Ser. B57 (1995) 289-300] procedure (BH) which compares more significant p-values with more stringent thresholds. One notable choice of the sequence {? i } is given by the BH critical values [Formula: see text], where q ? (0, 1) and z(?) is the quantile of a standard normal distribution. SLOPE aims to provide finite sample guarantees on the selected model; of special interest is the false discovery rate (FDR), defined as the expected proportion of irrelevant regressors among all selected predictors. Under orthogonal designs, SLOPE with ?BH provably controls FDR at level q. Moreover, it also appears to have appreciable inferential properties under more general designs X while having substantial power, as demonstrated in a series of experiments running on both simulated and real data.

SUBMITTER: Bogdan M 

PROVIDER: S-EPMC4689150 | biostudies-literature | 2015

REPOSITORIES: biostudies-literature